Desmopressin is a vasopressin analogue used for diabetes insipidus and bleeding disorders (DDAVP).
10 listed companies hold an active US Type II Drug Master File for Desmopressin API, based in India (4), Netherlands (2), China (2), Spain (1), Switzerland (1). 10 have a regulator record of GMP manufacturing.
Ordered by score. Scores follow the published rules and are not affected by paid placement. Updated 2026-11-13.
Source: FDA Drug Master File list. Holding a DMF is a regulatory filing, not an FDA approval.
Aspen Pharmacare's API site in Oss, Netherlands, with roots in 1923; makes peptides with a liquid-phase process plus hormones and heparin. Holds US DMFs for 4 peptide APIs.
Peptide API subsidiary of Aurobindo Pharma with a plant near Hyderabad. Makes generic peptide APIs and runs GMP contract projects from mg to kg scale.
Privately owned Barcelona peptide CDMO founded in 1989, making GMP generic peptide APIs and custom NCE peptides. Holds US DMFs for 10 peptide APIs.
Indian CDMO whose Turbhe, Navi Mumbai site develops and makes peptide APIs by solid- and solution-phase synthesis. Holds US DMFs for 9 peptide APIs.
Raichur API and CDMO subsidiary of Shilpa Medicare; US DMFs for desmopressin, liraglutide and octreotide; Raichur units inspected by US FDA in 2025.
Jiangsu peptide CDMO and generic API supplier with large automated SPPS capacity; states it has passed four US FDA inspections. Holds US DMFs for 9 peptide APIs.
Dutch holding entity of TAPI, Teva's API and CDMO business, with peptide development and GMP production across a global plant network. Holds US DMFs for 9 peptide APIs.
Chinese peptide drug manufacturer producing APIs and finished products.
Peptide-focused CDMO running GMP manufacturing sites on three continents.
Mumbai peptide API maker acquired by Piramal Pharma in 2021; its oxytocin API is WHO-prequalified; US DMF for oxytocin.
Companies holding active US DMFs for Desmopressin include Aspen Oss B.V. (Aspen API), Auro Peptides Ltd, BCN Peptides SA, Piramal Pharma Ltd (Piramal Pharma Solutions), Shilpa Pharma Lifesciences Ltd, Sinopep-Allsino Biopharmaceutical Co., Ltd., TAPI NL B.V. (TAPI), Hybio Pharmaceutical, PolyPeptide Group and Hemmo Pharmaceuticals Pvt Ltd (Piramal Pharma Solutions). Other manufacturers may supply it without a US DMF.
Among listed DMF holders: India (4), Netherlands (2), China (2), Spain (1), Switzerland (1).
No. FDA reviews a DMF when a drug application references it and does not approve DMFs on their own.